TO STUDY CORRELATION OF INSULIN RESISTANCE WITH PHYSICAL ACTIVITY IN CHILDREN / ADOLESCENTS

Objective: IR is a pathological condition strongly associated with obesity and involved in the pathogenesis of T2D. The treatment insulin resistant children firstly targeted to lifestyle interventions. Homeostasis model assessment resistance (HOMA-IR) may be useful for early evaluation teenagers could have long-term benefit preventive diagnostic therapeutic intervention. Method: A cross-sectional study was performed on 80 adolescents age 5 14 years, 40 them were apparently healthy Body mass index (BMI) < 85th percentile 16 overweight BMI>85th below 95th 24 obese > percentile. Physical activity classified basis WHO guidelines. Out 33 active 47 less active. After overnight fasting 8 hr, blood samples taken serum glucose analysed. Insulin assessed by homeostasis assessment. Result Conclusion: Our results revealed altered values HOMA-IR high BMI mean decrease physical activity. We concluded that more studies should conducted focus preventing identifying risk factors children.